Visualizing the structures of biological molecular machines is an absolute requirement in order to understand their mechanism. Cryo-EM is a key method for this visualization, and due to the recent technical developments it can provide refined atomic structures even for structure-based drug design. The symposium coincides with the Nobel Prize that has been awarded for the development of the cryo-EM and will present the methodological progress as well as the applications to central biological questions. It brings together world-leading experts, Swedish researchers, and industrial scientists to discuss ideas for further advancement in this exciting and rapidly evolving field.

 

The Nobel Lectures given by this year’s Nobel Laureates in Physics and Chemistry will be held 9.00-14.00, December 8, Aula Magna, Stockholm University.

 

List of confirmed speakers

Nigel Unwin, MRC Laboratory of Molecular Biology, The structural basis of fast synaptic transmission explored by Cryo-EM 

Marin van Heel, Leiden University and LNNano, Campinas Brazil, TBA

Yoshinori Fujiyoshi, Nagoya University, Structure-guided drug development by Cryo-EM

Hongwei Wang, Tsinghua University, New opportunities that the phase plate brings to Cryo-EM

Peijun Zhang, University of Oxford and eBIC, Diamond Light Source, Structural Basis of HIV Capsid Assembly, Maturation and Host Cell Interactions

Christian Spahn, Charité-Universitätsmedizin, Germany, The ribosome - a paradigm for a macromolecular machine

Chris Russo, MRC Laboratory of Molecular Biology, Determining and avoiding some of the physical limits in electron cryomicroscopy

Dan Shi, Howard Hughes Medical Institute, MicroED – a new application of electron crystallography in structural biology

Shintaro Aibara, SciLifeLab / Stockholm University, From pharmaceutical compounds to ribosomes

Bjorn Forsberg, SciLifeLab / Stockholm, This changes everything: current and future processing paradigms in cryo-EM

Janna Bigalke, AstraZeneca Pharmaceuticals, Möndal, The secret to cell regeneration: structural basis for RET activation by Neurturin

Hongyi Xu, Stockholm University, Electron crystallography for studying protein structures

 

 

The symposium is free of charge but requires registration. All researchers are welcome to take active part and contribute with posters.

 

Date and time: 9.00-17.30, December 9, 2017

Venue: Arrhenius Laboratory, Stockholm University

Address: Svante Arrhenius Väg 16, 106 91 Stockholm

 

Click to Register

Deadline for registration: November 20, 2017

 

 

Organisers:

Alexey Amunts (SciLifeLab & SU)

Hans Hebert (KTH & KI)

Sven Hovmöller (SU)

Erik Lindahl (SciLifeLab, SU & KTH)

Hongyi Xu (SU)

Xiaodong Zou (SU)